BP 897 (hydrochloride)
BP 897 hydrochloride is a potent and partial dopamine D3 receptor agonist and a weak D2 receptor antagonist. BP 897 hydrochloride displays a high affinity at the dopamine D3 receptor (Ki=0.92 nM) and a 70 times lower affinity at the D2 receptor (Ki=61 nM) [1].
Product Specifications
CAS Number
314776-92-6
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/BP_897.html
Purity
99.84
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
COC1=C(N2CCN(CCCCNC(C3=CC4=C(C=CC=C4)C=C3)=O)CC2)C=CC=C1.[H]Cl
Molecular Formula
C26H32ClN3O2
Molecular Weight
454.00
Precautions
H315, H319, H335
References & Citations
[1]Pilla M, et al. Selective inhibition of cocaine-seeking behaviour by a partial dopamine D3 receptor agonist. Nature. 1999 Jul 22;400 (6742) :371-5.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
D2 Receptor; D3 Receptor
Available Sizes
Frequently Asked Questions
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