BP 897 (hydrochloride)

BP 897 hydrochloride is a potent and partial dopamine D3 receptor agonist and a weak D2 receptor antagonist. BP 897 hydrochloride displays a high affinity at the dopamine D3 receptor (Ki=0.92 nM) and a 70 times lower affinity at the D2 receptor (Ki=61 nM) [1].

Product Specifications

CAS Number

[314776-92-6]

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Dopamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/BP_897.html

Purity

99.84

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

COC1=C(N2CCN(CCCCNC(C3=CC4=C(C=CC=C4)C=C3)=O)CC2)C=CC=C1.[H]Cl

Molecular Formula

C26H32ClN3O2

Molecular Weight

454.00

Precautions

H315, H319, H335

References & Citations

[1]Pilla M, et al. Selective inhibition of cocaine-seeking behaviour by a partial dopamine D3 receptor agonist. Nature. 1999 Jul 22;400 (6742) :371-5.