(Gly14) -Humanin (human) (acetate)

(Gly14) -Humanin (human) (14-Glycine-Humanin (human) ) acetate is an analog of Humanin in which the 14th amino acid serine was replaced with glycine (Gly) . (Gly14) -Humanin (human) acetate has anti-apoptotic and neuroprotective functions[1][2].

Product Specifications

Product Name Alternative

14-Glycine-Humanin (human) (acetate)

UNSPSC

12352209

Target

Apoptosis

Type

Peptides

Related Pathways

Apoptosis

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/gly14-humanin-human-acetate.html

Purity

99.86

Solubility

10 mM in DMSO

Smiles

[MAPRGFSCLLLLTGEIDLPVKRRA(acetate)]

Molecular Formula

C118H202N34O31S2.xC2H4O2

Molecular Weight

2657.21 (free acid)

References & Citations

[1]Ying Xie, et al. Protection effect of [Gly14]-Humanin from apoptosis induced by high glucose in human umbilical vein endothelial cells. Diabetes Res Clin Pract. 2014 Dec;106 (3) :560-6. |[2]T Wang, et al. [Gly14]-Humanin reduces histopathology and improves functional outcome after traumatic brain injury in mice. Neuroscience. 2013 Feb 12;231:70-81.