Cyanidin 3-sambubioside (chloride)

Cyanidin 3-sambubioside chloride (Cyanidin-3-O-sambubioside chloride), a major anthocyanin, a natural colorant, and is a potent NO inhibitor. Cyanidin 3-sambubioside chloride is a H274Y mutation inhibitor, and inhibits influenza neuraminidase activity with an IC50 of 72 μM. Cyanidin 3-sambubioside chloride inhibits angiotensin-converting enzyme (ACE) activity and has antioxidant, anti-angiogenic and antiviral properties[1][2][3].

Product Specifications

CAS Number

[33012-73-6]

Product Name Alternative

Cyanidin-3-O-sambubioside (chloride)

UNSPSC

12352005

Target

Akt; Angiotensin-converting Enzyme (ACE) ; Influenza Virus; MMP

Type

Natural Products

Related Pathways

Anti-infection; Metabolic Enzyme/Protease; PI3K/Akt/mTOR

Applications

COVID-19-anti-virus

Field of Research

Cancer; Infection; Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/cyanidin-3-sambubioside-chloride.html

Purity

98.40

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

OC1=CC(O)=CC2=C1C=C(C(C3=CC(O)=C(C=C3)O)=[O+]2)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O[C@H]5[C@@H]([C@H]([C@@H](CO5)O)O)O.[Cl-]

Molecular Formula

C26H29ClO15

Molecular Weight

616.95

References & Citations

[1]Jung-Chu Cheng, et al. Detection of cyanidin in different-colored peanut testae and identification of peanut cyanidin 3-sambubioside. J Agric Food Chem. 2009 Oct 14;57 (19) :8805-11.|[2]S Kannan, et al. The inhibitory performance of flavonoid cyanidin-3-sambubiocide against H274Y mutation in H1N1 influenza virus. J Biomol Struct Dyn. 2018 Dec;36 (16) :4255-4269.|[3]Sang-Jin Lee, et al. Cyanidin-3-O-sambubioside from Acanthopanax sessiliflorus fruit inhibits metastasis by downregulating MMP-9 in breast cancer cells MDA-MB-231. Planta Med. 2013 Nov;79 (17) :1636-40.