Dynamin inhibitory peptide (TFA)
Dynamin inhibitory peptide TFA competitively blocks binding of dynamin to amphiphysin, thus preventing endocytosis. Dynamin inhibitory peptide TFA blocks the dopamine D3 effect on GABAA receptors[1].
Product Specifications
UNSPSC
12352209
Target
Dynamin
Type
Peptides
Related Pathways
Cytoskeleton
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/dynamin-inhibitory-peptide-tfa.html
Solubility
H2O
Smiles
O=C(N[C@@H](C(C)C)C(N1[C@@H](CCC1)C(N[C@@H](CO)C(N[C@@H](CCCNC(N)=N)C(N2[C@@H](CCC2)C(N[C@@H](CC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C)C(N3[C@@H](CCC3)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCC(N)=O)N.O=C(O)C(F)(F)F
Molecular Formula
C49H81F3N18O16
Molecular Weight
1235.27
References & Citations
[1]Guojun Chen, et al. Dopamine D3 receptors regulate GABAA receptor function through a phospho-dependent endocytosis mechanism in nucleus accumbens. J Neurosci. 2006 Mar 1;26 (9) :2513-21.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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