Ixazomib citrate

Ixazomib citrate (MLN9708) is a selective, orally active, second-generation proteasome inhibitor. Ixazomib citrate can be used for the study of a broad range of human malignancies[1][2][3].

Product Specifications

CAS Number

[1239908-20-3]

Product Name Alternative

MLN9708

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Autophagy; Proteasome

Type

Reference compound

Related Pathways

Autophagy; Metabolic Enzyme/Protease

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/MLN9708.html

Concentration

10mM

Purity

99.89

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

O=C(O)CC1(CC(O)=O)OB([C@@H](NC(CNC(C2=CC(Cl)=CC=C2Cl)=O)=O)CC(C)C)OC1=O

Molecular Formula

C20H23BCl2N2O9

Molecular Weight

517.12

Precautions

H302, H315, H319, H335

References & Citations

[1]Demirbilek S, et al. Small-dose capsaicin reduces systemic inflammatory responses in septic rats. Anesth Analg. 2004 Nov;99 (5) :1501-1507.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Launched

Available Sizes

Curated Selection

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