Ixazomib citrate
Product Specifications
UNSPSC Description
Ixazomib citrate (MLN9708) is a reversible inhibitor of the chymotrypsin-like proteolytic β5 site of the 20S proteasome with an IC50 of 3.4 nM and a Ki of 0.93 nM.
Target Antigen
Autophagy; Proteasome
Type
Reference compound
Related Pathways
Autophagy;Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/MLN9708.html
Purity
99.89
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(O)CC1(CC(O)=O)OB([C@@H](NC(CNC(C2=CC(Cl)=CC=C2Cl)=O)=O)CC(C)C)OC1=O
Molecular Weight
517.12
References & Citations
[1]Demirbilek S, et al. Small-dose capsaicin reduces systemic inflammatory responses in septic rats. Anesth Analg. 2004 Nov;99(5):1501-1507.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-10452/Ixazomib-citrate-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-10452/Ixazomib-citrate-SDS-MedChemExpress.pdf
Clinical Information
Launched
CAS Number
1239908-20-3
Available Sizes
Curated Selection
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