Physostigmine (hemisulfate)
Physostigmine hemisulfate (Eserine hemisulfate) is a reversible acetylcholinesterase (AChE) inhibitor. Physostigmine hemisulfate can crosses the blood-brain barrier and stimulates central cholinergic neurotransmission. Physostigmine hemisulfate can reverse memory deficits in transgenic mice with Alzheimer's disease. Physostigmine hemisulfate is also an antidote for anticholinergic poisoning[1][2][3][4].
Product Specifications
CAS Number
64-47-1
Product Name Alternative
Eserine (hemisulfate)
UNSPSC
12352005
Hazard Statement
H300+H330
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/physostigmine-hemisulfate.html
Purity
99.0
Solubility
H2O : 50 mg/mL (ultrasonic)
Smiles
CN1[C@](N(C)CC2)([H])[C@]2(C)C3=C1C=CC(OC(NC)=O)=C3.O=S(O)(O)=O.[1/2]
Molecular Formula
C15H21N3O2.1/2H2O4S
Molecular Weight
324.38
Precautions
P260-P264-P270-P271-P284-P304+P340-P330-P403+P233-P405-P501
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Phase 4
Isoform
AChE
Available Sizes
Frequently Asked Questions
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