GNF6702
Product Specifications
UNSPSC Description
GNF6702 is a selective inhibitor of the kinetoplastid proteasome. GNF6702 clears parasites in murine models of leishmaniasis, Chagas disease, and human African trypanosomiasis[1].
Target Antigen
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/gnf6702.html
Purity
98.48
Solubility
DMSO : 10 mg/mL (ultrasonic;warming;heat to 80°C)
Smiles
O=C(C1=C(C)N=C(C)O1)NC2=CC=C(F)C(C3=NN4C=C(C5=NC=CC=C5)C=NC4=N3)=C2
Molecular Weight
429.41
References & Citations
[1]Nagle A, et al. Discovery and Characterization of Clinical Candidate LXE408 as a Kinetoplastid-Selective Proteasome Inhibitor for the Treatment of Leishmaniases. J Med Chem. 2020;63(19):10773-10781.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-120060/GNF6702-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-120060/GNF6702-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1799329-72-8
Available Sizes
Curated Selection
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