Ethyl 7- (diethylamino) -2-oxo-2H-chromene-3-carboxylate
Ethyl 7- (diethylamino) -2-oxo-2H-chromene-3-carboxylate is a potent and selective inhibitor of hMAO-B with an IC50 of 45.52 μM[1].
Product Specifications
CAS Number
[28705-46-6]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Monoamine Oxidase
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ethyl-7-diethylamino-2-oxo-2h-chromene-3-carboxylate.html
Purity
99.94
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(C1=CC2=CC=C(N(CC)CC)C=C2OC1=O)OCC
Molecular Formula
C16H19NO4
Molecular Weight
289.33
Precautions
H302, H315, H319, H335
References & Citations
[1]Secci D, et al. Synthesis and selective human monoamine oxidase inhibition of 3-carbonyl, 3-acyl, and 3-carboxyhydrazido coumarin derivatives. Eur J Med Chem. 2011 Oct;46 (10) :4846-52.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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