(±) -Coniine (hydrochloride)
(±) -Coniine hydrochloride (2-Propylpiperidine hydrochloride) is a potent nAChR agonist with an EC50 value of 0.3 mM. (±) -Coniine hydrochloride shows acute toxicity with an LD50 value of 7.7 mg/kg[1].
Product Specifications
CAS Number
[15991-59-0]
Product Name Alternative
2-Propylpiperidine (hydrochloride)
UNSPSC
12352005
Hazard Statement
H300+H310+H330
Target
NAChR
Type
Natural Products
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/racemic-coniine-hydrochloride.html
Purity
98.0
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
CCCC1CCCCN1.Cl
Molecular Formula
C8H18ClN
Molecular Weight
163.69
Precautions
H300+H310+H330
References & Citations
[1]Lee ST, et al. Stereoselective potencies and relative toxicities of coniine enantiomers. Chem Res Toxicol. 2008 Oct;21 (10) :2061-4.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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