Cefonicid (sodium)

Cefonicid sodium is a broadspectrum cephalosporin antibiotic which inhibits the formation of the bacterial cell wall. Target: Antibacterial Cefonicid sodium can inhibit the carnitine/carnitine antiport when it is added internally and externally to proteoliposomes. It is known that the molecule contains various electroactive groups that can be detected using adsorptive square-wave stripping voltammetry. In addition, the compound can be detected in solution using UV spectroscopy at 265 nm. Cefonicid sodium is effective against Escherichia coli, Klebsiella, Citrobacter, Enterobacter, indole-negative Proteus, and Providencia.

Product Specifications

CAS Number

[61270-78-8]

UNSPSC

12352005

Hazard Statement

H317, H334

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/Cefonicid-sodium.html

Purity

98.02

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(C(N12)=C(CSC3=NN=NN3CS(=O)(O[Na])=O)CS[C@]2([H])[C@H](NC([C@H](O)C4=CC=CC=C4)=O)C1=O)O[Na]

Molecular Formula

C18H16N6Na2O8S3

Molecular Weight

586.53

Precautions

H317, H334

References & Citations

[1]Saltiel E, et al. Cefonicid. A review of its antibacterial activity, pharmacological properties and therapeutic use. Drugs. 1986 Sep;32 (3) :222-59.|[2]Dudley MN, et al. Review of cefonicid, a long-acting cephalosporin. Clin Pharm. 1984 Jan-Feb;3 (1) :23-32.