Human CCL4 Protein, His Tag
Human CCL4 Protein, His Tag (CC4-H51H3) is expressed from E. coli cells. It contains AA Ala 24 - Asn 92 (Accession # P13236-1) .
Product Specifications
Background
CCL4, also know as MIP-1-beta, is monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV) . The processed form MIP-1-beta (3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta (3-69) is also a ligand for CCR1 and CCR2 isoform B
Specifications
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 9.7 kDa.
Accession Number
P13236-1
Expression Region
Ala 24 - Asn 92
Host
E. coli
Origin Species
Human
Target
CCL4
Conjugation
Unconjugated
Tag
C-10xHis
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Format
Powder
Molecular Weight
9.7 kDa
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
100ug*1
Species
Human
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