Eldacimibe
Eldacimibe is an ACAT2 inhibitor. Eldacimibe can lower plasma cholesterol levels by blocking cholesterol absorption and can prevent macrophages from turning into foam cells. Eldacimibe can be used in the study of cardiovascular diseases (atherosclerosis), endocrine and metabolic diseases (hypercholesterolemia) [1].
Product Specifications
CAS Number
[141993-70-6]
Product Name Alternative
WAY-ACA 147
UNSPSC
12352005
Target
Acyltransferase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/eldacimibe.html
Solubility
10 mM in DMSO
Smiles
CC(C)(CC1=CC=C(CN(/C(NC2=CC(C(C)(C)C)=C(C(C(C)(C)C)=C2)O)=C3C(OC(C)(OC\3=O)C)=O)CCCCCC)C=C1)C
Molecular Formula
C39H58N2O5
Molecular Weight
634.89
References & Citations
[1]Chhabria M T, et al. Update on patented cholesterol absorption inhibitors[J]. Expert Opinion on Therapeutic Patents, 2009, 19 (8) : 1083-1107.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
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