Eldacimibe

Eldacimibe is an ACAT2 inhibitor. Eldacimibe can lower plasma cholesterol levels by blocking cholesterol absorption and can prevent macrophages from turning into foam cells. Eldacimibe can be used in the study of cardiovascular diseases (atherosclerosis), endocrine and metabolic diseases (hypercholesterolemia) [1].

Product Specifications

CAS Number

[141993-70-6]

Product Name Alternative

WAY-ACA 147

UNSPSC

12352005

Target

Acyltransferase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/eldacimibe.html

Solubility

10 mM in DMSO

Smiles

CC(C)(CC1=CC=C(CN(/C(NC2=CC(C(C)(C)C)=C(C(C(C)(C)C)=C2)O)=C3C(OC(C)(OC\3=O)C)=O)CCCCCC)C=C1)C

Molecular Formula

C39H58N2O5

Molecular Weight

634.89

References & Citations

[1]Chhabria M T, et al. Update on patented cholesterol absorption inhibitors[J]. Expert Opinion on Therapeutic Patents, 2009, 19 (8) : 1083-1107.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 2

Available Sizes

Curated Selection

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