Methyl 2,5-dihydroxycinnamate
Methyl 2,5-dihydroxycinnamate is an erbstatin analog and a stable, potent inhibitor of EGFR kinase activity[1].
Product Specifications
CAS Number
[63177-57-1]
UNSPSC
12352005
Hazard Statement
H315, H319
Target
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/methyl-2-5-dihydroxycinnamate.html
Concentration
10mM
Purity
99.77
Solubility
DMSO : 125 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(OC)/C=C/C1=CC(O)=CC=C1O
Molecular Formula
C10H10O4
Molecular Weight
194.19
Precautions
H315, H319
References & Citations
[1]Umezawa K, et al. Inhibition of epidermal growth factor-induced DNA synthesis by tyrosine kinase inhibitors. FEBS Lett. 1990 Jan 29;260 (2) :198-200.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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