Halo-DBCO
Product Specifications
UNSPSC Description
Halo-DBCO is a click chemistry reagent containing dibenzocyclooctyne (DBCO). Halo-DBCO can be used as a ligand to react with HaloTag to form covalent HaloTag ligand couples[1].
Target Antigen
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/halo-dbco.html
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(CCC(N1C2=C(C#CC3=C(C1)C=CC=C3)C=CC=C2)=O)NCCOCCOCCCCCCCl
Molecular Weight
511.05
References & Citations
[1]Teng X, et al. ClickRNA-PROTAC for Tumor-Selective Protein Degradation and Targeted Cancer Therapy. J Am Chem Soc. 2024 Oct 9;146(40):27382-27391.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-151716/Halo-DBCO-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-151716/Halo-DBCO-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1808119-16-5
Available Sizes
Curated Selection
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