Halo-DBCO

Halo-DBCO is a click chemistry reagent containing dibenzocyclooctyne (DBCO) . Halo-DBCO can be used as a ligand to react with HaloTag to form covalent HaloTag ligand couples[1].

Product Specifications

CAS Number

[1808119-16-5]

UNSPSC

12352005

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/halo-dbco.html

Concentration

10mM

Purity

98.25

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(CCC(N1C2=C(C#CC3=C(C1)C=CC=C3)C=CC=C2)=O)NCCOCCOCCCCCCCl

Molecular Formula

C29H35ClN2O4

Molecular Weight

511.05

References & Citations

[1]Teng X, et al. ClickRNA-PROTAC for Tumor-Selective Protein Degradation and Targeted Cancer Therapy. J Am Chem Soc. 2024 Oct 9;146 (40) :27382-27391.