Halo-DBCO
Halo-DBCO is a click chemistry reagent containing dibenzocyclooctyne (DBCO) . Halo-DBCO can be used as a ligand to react with HaloTag to form covalent HaloTag ligand couples[1].
Product Specifications
CAS Number
[1808119-16-5]
UNSPSC
12352005
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/halo-dbco.html
Concentration
10mM
Purity
98.25
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(CCC(N1C2=C(C#CC3=C(C1)C=CC=C3)C=CC=C2)=O)NCCOCCOCCCCCCCl
Molecular Formula
C29H35ClN2O4
Molecular Weight
511.05
References & Citations
[1]Teng X, et al. ClickRNA-PROTAC for Tumor-Selective Protein Degradation and Targeted Cancer Therapy. J Am Chem Soc. 2024 Oct 9;146 (40) :27382-27391.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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