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LY329146

Product Specifications

UNSPSC Description

LY329146, a Raloxifene (HY-13738) analog, is multidrug resistance protein (MRP1) inhibitor. LY329146 inhibits leucotriene C4 ( LTC4) transport with an IC50 of 0.8 μM[1].

Target Antigen

Leukotriene Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ly329146.html

Smiles

CS(=O)(N(C1=CC=C(C2=C(C(C3=CC=C(OCCN4CCCCC4)C=C3)=O)C5=CC=C(O)C=C5S2)C=C1)S(=O)(C)=O)=O

Molecular Weight

628.78

References & Citations

[1]H Sun, et al. Effect of probenecid on fluorescein transport in the central nervous system using in vitro and in vivo models. Pharm Res. 2001 Nov;18(11):1542-9.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-120931/LY329146-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-120931/

Clinical Information

No Development Reported

CAS Number

191043-78-4

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