Head activator neuropeptide

Head activator neuropeptide is a mitogen for mammalian cell lines of neuronal or neuroendocrine origin. Head activator neuropeptide signals by binding GPR37 and stimulates cells to enter mitosis[1].

Product Specifications

CAS Number

[79943-68-3]

UNSPSC

12352209

Target

Mitosis; Orphan Receptor

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

Cancer-programmed cell death

Field of Research

Cancer; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/head-activator-neuropeptide.html

Purity

99.50

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(N1[C@@H](CCC1)C(N2[C@@H](CCC2)C(NCC(NCC(N[C@@H](CO)C(N[C@@H](CCCCN)C(N[C@@H](C(C)C)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(C)C)C(N[C@@H](CC3=CC=CC=C3)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC4)NC4=O

Molecular Formula

C54H84N12O14

Molecular Weight

1125.32

References & Citations

[1]Rezgaoui M, et al. The neuropeptide head activator is a high-affinity ligand for the orphan G-protein-coupled receptor GPR37. J Cell Sci. 2006 Feb 1;119 (Pt 3) :542-9.