BP 897
BP 897 is a potent and partial dopamine D3 receptor agonist and a weak D2 receptor antagonist. BP 897 displays a high affinity at the dopamine D3 receptor (Ki=0.92 nM) and a 70 times lower affinity at the D2 receptor (Ki=61 nM) [1].
Product Specifications
CAS Number
[192384-87-5]
Product Name Alternative
Nanchangmycin A
UNSPSC
12352005
Target
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bp-897.html
Solubility
10 mM in DMSO
Smiles
COC1=C(N2CCN(CCCCNC(C3=CC4=C(C=CC=C4)C=C3)=O)CC2)C=CC=C1
Molecular Formula
C26H31N3O2
Molecular Weight
417.54
References & Citations
[1]Pilla M, et al. Selective inhibition of cocaine-seeking behaviour by a partial dopamine D3 receptor agonist [published correction appears in Nature 1999 Sep 23;401 (6751) :403]. Nature. 1999;400 (6742) :371-375.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
D2 Receptor; D3 Receptor
Available Sizes
Curated Selection
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