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BP 897

Product Specifications

Product Name Alternative

Nanchangmycin A

UNSPSC Description

BP 897 is a potent and partial dopamine D3 receptor agonist and a weak D2 receptor antagonist. BP 897 displays a high affinity at the dopamine D3 receptor (Ki=0.92 nM) and a 70 times lower affinity at the D2 receptor (Ki=61 nM)[1].

Target Antigen

Dopamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein;Neuronal Signaling

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/bp-897.html

Solubility

10 mM in DMSO

Smiles

COC1=C(N2CCN(CCCCNC(C3=CC4=C(C=CC=C4)C=C3)=O)CC2)C=CC=C1

Molecular Weight

417.54

References & Citations

[1]Pilla M, et al. Selective inhibition of cocaine-seeking behaviour by a partial dopamine D3 receptor agonist [published correction appears in Nature 1999 Sep 23;401(6751):403]. Nature. 1999;400(6742):371-375.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-114085/BP-897-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-114085/

Clinical Information

Phase 2

CAS Number

192384-87-5

Available Sizes

Curated Selection

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