di-Pal-MTO
Product Specifications
UNSPSC Description
di-Pal-MTO is a palm oil-based lipid produced by combining the anticancer agent mitoxantrone (MTO) with palmitoleic acid. When nanoparticles of mono-Pal-MTO and di-Pal-MTO are combined in a molar ratio of 1:1, they show effective siRNA cell delivery and enhance anticancer activity[1].
Target Antigen
Liposome
Type
Oligonucleotides
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/di-pal-mto.html
Solubility
DMSO : 10 mg/mL (ultrasonic)
Smiles
CCCCCC/C=C\CCCCCCCC(OCCNCCNC1=C2C(C(C3=C(O)C=CC(O)=C3C2=O)=O)=C(C=C1)NCCNCCOC(CCCCCCC/C=C\CCCCCC)=O)=O
Molecular Weight
917.27
References & Citations
[1]Rae Sung Chang, et al. Cationic drug-derived nanoparticles for multifunctional delivery of anticancer siRNA. Biomaterials. 2011 Dec;32(36):9785-95.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-148702/di-Pal-MTO-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-148702/di-Pal-MTO-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1349197-90-5
Available Sizes
Curated Selection
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