4-Nitrophenyl 4-guanidinobenzoate (hydrochloride)
4-Nitrophenyl 4-guanidinobenzoate (NPGB) hydrochloride is a potent sperm acrosin inhibitor, and also a trypsin substrate[1].
Product Specifications
CAS Number
[19135-17-2]
Product Name Alternative
NPGB (hydrochloride)
UNSPSC
12352005
Hazard Statement
H318
Target
Ser/Thr Protease
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/4-nitrophenyl-4-guanidinobenzoate-hydrochloride.html
Purity
99.38
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 80°C)
Smiles
O=C(OC1=CC=C([N+]([O-])=O)C=C1)C2=CC=C(NC(N)=N)C=C2.[H]Cl
Molecular Formula
C14H13ClN4O4
Molecular Weight
336.73
Precautions
P280-P305+P351+P338
References & Citations
[1]J M Kaminski, et al. Synthesis and inhibition of human acrosin and trypsin and acute toxicity of aryl 4-guanidinobenzoates. J Med Chem. 1986 Apr;29 (4) :514-9.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
LH15197V 100 µg
RING finger protein 175 (RNF175) (NM_173662) Human Over-expression Lysate
Ask
View Details 
GTR15246456 1 Vial
Lentiviral mouse Cacng8 shRNA (UAS) - Lentiviral mouse Cacng8 shRNA (UAS, RFP) (100)
Ask
View Details 
GTR15241301 1 Vial
Lentiviral mouse Fam187a shRNA (UAS) - Lentiviral mouse Fam187a shRNA (UAS) (25)
Ask
View Details