Botryodiplodin

Botryodiplodin is a mycotoxin isolated from Penicillium roqueforti. Botryodiplodin inhibits the growth of some Gram-positive and Gram-negative bacteria and can also induce DNA-protein cross-links in mammalian cells, inhibiting the synthesis of DNA, RNA, and protein[1][2].

Product Specifications

CAS Number

[27098-03-9]

UNSPSC

12352005

Target

Bacterial; DNA/RNA Synthesis

Type

Reference compound

Related Pathways

Anti-infection; Cell Cycle/DNA Damage

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/botryodiplodin.html

Smiles

O=C(C)[C@H]1[C@H](C(OC1)O)C

Molecular Formula

C7H12O3

Molecular Weight

144.17

References & Citations

[1]Moulé Y, et al. DNA-protein cross-linking by the mycotoxin, botryodiplodin, in mammalian cells[J]. Carcinogenesis, 1982, 3 (2) : 211-214.|[2]Moulé Y, et al. Mutagenicity of the mycotoxin botryodiplodin in the Salmonella typhimurium/microsomal activation test[J]. Environmental Mutagenesis, 1981, 3 (3) : 287-291.