Kainic acid (hydrate)

Kainic acid hydrate is a potent excitotoxic agent. Kainic acid hydrate also is an agonist for a subtype of ionotropic glutamate receptor. Kainic acid hydrate induces seizures[1][2].

Product Specifications

CAS Number

[58002-62-3]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

MGluR

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/kainic-acid-hydrate.html

Solubility

10 mM in DMSO

Smiles

O=C(O)C[C@@H]1[C@@H](C(O)=O)NC[C@@H]1C(C)=C.O

Molecular Formula

C10H17NO5

Molecular Weight

231.25

Precautions

H302, H315, H319, H335

References & Citations

[1]Cincioğlu-Palabiyik M, et al. Chronic levetiracetam decreases hippocampal and testicular aromatase expression in normal but not kainic acid-induced experimental model of acute seizures in rats. Neuroreport. 2017 Sep 27;28 (14) :903-909.|[2]Wang Q, et al. Kainic acid-mediated excitotoxicity as a model for neurodegeneration. Mol Neurobiol. 2005;31 (1-3) :3-16.