Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

B I09

B I09 is an IRE-1 RNase inhibitor, with an IC50 of 1230 nM.

Product Specifications

CAS Number

1607803-67-7

UNSPSC

12352005

Target

IRE1

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/B_I09.html

Purity

99.35

Solubility

DMSO : 11.11 mg/mL (ultrasonic)

Smiles

OC1=CC=C(C2=C(CNCC2)C3=O)C(O3)=C1C4OCCCO4

Molecular Formula

C16H17NO5

Molecular Weight

303.31

References & Citations

[1]Ranatunga S, et al. Synthesis of novel tricyclic chromenone-based inhibitors of IRE-1 RNase activity. J Med Chem. 2014 May 22;57 (10) :4289-301.|[2]Tang CH, et al. Inhibition of ER stress-associated IRE-1/XBP-1 pathway reduces leukemic cell survival. J Clin Invest. 2014 Jun;124 (6) :2585-98.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Tube Rack
R1050 5 Units/Pack

Tube Rack

Sign In for Pricing
View Details
NAPG (Center) Rabbit Polyclonal Antibody
AP52808PU-N 400 µL

NAPG (Center) Rabbit Polyclonal Antibody

Sign In for Pricing
View Details
HOXA9 (C-term) Rabbit Polyclonal Antibody
AP52077PU-N 400 µL

HOXA9 (C-term) Rabbit Polyclonal Antibody

Sign In for Pricing
View Details
MKRN2OS Human Gene Knockout Kit (CRISPR)
KN431069 1 Kit

MKRN2OS Human Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details
AKT2 Rat Monoclonal Antibody [Clone ID: 11F6.B2]
TA397077 50 µg

AKT2 Rat Monoclonal Antibody [Clone ID: 11F6.B2]

Sign In for Pricing
View Details
ATP5MC1 Human Gene Knockout Kit (CRISPR)
KN400292 1 Kit

ATP5MC1 Human Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details