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IMMH-010 (maleate)

IMMH-010 maleate is a prodrug that serves as a novel PD-L1 inhibitor, exhibiting potential antitumor activity for the treatment of neurological disorders and advanced malignant solid tumors. IMMH-010 maleate is rapidly converted to its active form, YPD-29B, following oral administration. IMMH-010 maleate is poised for advancing research in the field of PD-L1 inhibitors and related therapeutic applications.

Product Specifications

CAS Number

2541982-47-0

UNSPSC

12352101

Target

PD-1/PD-L1

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/immh-010-maleate.html

Purity

99.80

Smiles

OC(/C=C\C(O)=O)=O.CC(C)OC([C@H](CO)NCC(C=C(C(OCC1=C(C(C2=CC=CC=C2)=CC=C1)Br)=C3)Cl)=C3OCC4=CN=CC=C4)=O

Molecular Formula

C36H36BrClN2O9

Molecular Weight

756.04

References & Citations

[1]Simultaneous Determination of a Novel PD-L1 Inhibitor, IMMH-010, and Its Active Metabolite, YPD-29B, in Rat Biological Matrices by Polarity-Switching Liquid Chromatography-Tandem Mass Spectrometry: Application to ADME Studies

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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