YM-31636 (free base)
YM-31636 free base is an orally active, potent and selective 5-HT3 receptor agonist with a Ki value of 0.2 nM. YM-31636 free base induces contraction of isolated guinea pig distal colon. YM-31636 free base induces tachycardia with the relative intrinsic activity of approximately 0.23 in isolated guinea pig right atrium. YM-31636 free base is promising for research of constipation[1][2].
Product Specifications
CAS Number
159081-22-8
UNSPSC
12352005
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ym-31636-free-base.html
Concentration
10mM
Purity
99.05
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C1(CC2=NC3=C(S2)CC4=C3C=CC=C4)=CN=CN1
Molecular Formula
C14H11N3S
Molecular Weight
253.32
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Lactoferrin; mLAG-3; α-1 microglobulin
Available Sizes
Frequently Asked Questions
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