MR2034

MR2034 ((R) -UM-1071) is a κ-opioid receptor agonist with activity that stimulates the hypothalamic-pituitary-adrenal axis. MR2034 has shown the potential to promote mood and inhibit addictive behaviors in animal models and can be used to study inhibitory approaches related to mood and addictive disorders. MR2034 is selective for κ-opioid receptors and can effectively modulate biological processes related to stress and mood[1].

Product Specifications

CAS Number

[57236-85-8]

Product Name Alternative

(R) -UM-1071

UNSPSC

12352005

Target

Opioid Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/mr2034.html

Smiles

C[C@]12C3=CC(O)=CC=C3C[C@](N(CC2)C[C@H]4CCCO4)([H])[C@@H]1C

Molecular Formula

C19H27NO2

Molecular Weight

301.42

References & Citations

[1]LY2456302 is a novel, potent, orally-bioavailable small molecule kappa-selective antagonist with activity in animal models predictive of efficacy in mood and addictive disorders