XH161-180
XH161-180 is a potent and orally active ubiquitin carboxyl-terminal hydrolase 2 (USP2) inhibitor. XH161-180 decreases the protein of cyclin D and ACE2. XH161-180 shows antiproliferative activity. XH161-180 has the potential for the research of cancer and virus infection depending on ACE2[1].
Product Specifications
CAS Number
[3058588-52-3]
UNSPSC
12352005
Target
Deubiquitinase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/xh161-180.html
Smiles
O=C(NC1=NC(C2=CC=C(Br)C=C2)=CS1)C3=CC=C(F)C=C3NS(=O)(C4CCCCC4)=O
Molecular Formula
C22H21BrFN3O3S2
Molecular Weight
538.45
References & Citations
[1]Jian Jin, et al. Usp2 inhibitors and methods of using the same for the treatment of diseases. French, WO2024211785A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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