Ubiquitin-Specific Protease 8 Human

<strong>Ubiquitin-Specific Protease 8 Human</strong>_x000D_ <strong>Catalog number:</strong> B2019677_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> 128 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> −70°C_x000D_ <strong>Keywords:</strong> Ubiquitin-Specific Protease 8 Human_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Yang H, Zhang X, Lao M, Sun K, He L, Xu J, Duan Y, Chen Y, Ying H, Li M, Guo C, Lu Q, Wang S, Su W, Liang T, Bai X. Targeting ubiquitin-specific protease 8 sensitizes anti-programmed death-ligand 1 immunotherapy of pancreatic cancer Cell Death Differ. 2023 Feb;30(2):560-575._x000D_ 2: Peng H, Yang F, Hu Q, Sun J, Peng C, Zhao Y, Huang C. The ubiquitin-specific protease USP8 directly deubiquitinates SQSTM1/p62 to suppress its autophagic activity Autophagy. 2020 Apr;16(4):698-708._x000D_ 3: Liu L, Huan L, Zhang Y, Wei W, Chen Z, Xu D, Huang X, Tan Y, Li H. Ubiquitin-specific protease 8 inhibits lipopolysaccharide-triggered pyroptosis of human bronchial epithelial cells by regulating PI3K/AKT and NF-κB pathways Allergol Immunopathol (Madr). 2022 Mar 1;50(2):96-103._x000D_ 4: Yang Z, Nicholas J. Biologically significant interaction of human herpesvirus 8 viral interferon regulatory factor 4 with ubiquitin-specific protease 7 J Virol. 2024 Jun 13;98(6):e0025524._x000D_ 5: Jutant EM, Chelgham MK, Ottaviani M, Thuillet R, Le Vely B, Humbert M, Guignabert C, Tu L, Huertas A. Central role of ubiquitin-specific protease 8 in leptin signaling pathway in pulmonary arterial hypertension J Heart Lung Transplant. 2024 Jan;43(1):120-133._x000D_ 6: Dufner A, Knobeloch KP. Ubiquitin-specific protease 8 (USP8/UBPy): a prototypic multidomain deubiquitinating enzyme with pleiotropic functions Biochem Soc Trans. 2019 Dec 20;47(6):1867-1879._x000D_ 7: Zhou CJ, Zhang C, Lu LF, Li S. Fish ubiquitin-specific protease 8 (USP8) inhibits IFN production through autophagy-lysosomal dependent degradation of IRF7 Dev Comp Immunol. 2024 Jul;156:105181._x000D_ 8: Ghosh DK, Ranjan A. HYPK coordinates degradation of polyneddylated proteins by autophagy Autophagy. 2022 Aug;18(8):1763-1784._x000D_ 9: Sun Q, Zhang J, Li X, Yang G, Cheng S, Guo D, Zhang Q, Sun F, Zhao F, Yang D, Wang S, Wang T, Liu S, Zou L, Zhang Y, Liu H. The ubiquitin-specific protease 8 antagonizes melatonin-induced endocytic degradation of MT(1) receptor to promote lung adenocarcinoma growth J Adv Res. 2022 Nov;41:1-12._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/37287426">10: Zeng M, Wei X, He Y, Yang Y. Ubiquitin-specific protease 11-mediated CD36 deubiquitination acts on C1q/TNF-related protein 9 against atherosclerosis ESC Heart Fail. 2023 Aug;10(4):2499-2509. </a>_x000D_ _x000D_ <strong>Products Related to Ubiquitin-Specific Protease 8 Human can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>