(±) -Coniine
(±) -Coniine (2-Propylpiperidine) is a piperidine alkaloid and nAChR agonist (EC50=0.3 mM) . (±) -Coniine is acutely toxic to mice with an LD50 value of 7.7 mg/kg[1][2].
Product Specifications
CAS Number
[3238-60-6]
Product Name Alternative
2-Propylpiperidine
UNSPSC
12352005
Hazard Statement
H315-H319-H320
Target
NAChR
Type
Natural Products
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/racemic-coniine.html
Solubility
10 mM in DMSO
Smiles
CCCC1NCCCC1
Molecular Formula
C8H17N
Molecular Weight
127.23
Precautions
P264-P280-P302+P352-P305+P351+P338-P362
References & Citations
[1]B T Green, et al. Complete Inhibition of Fetal Movement in the Day 40 Pregnant Goat Model by the Piperidine Alkaloid Anabasine but Not Related Alkaloids. Toxicon. 2018 Mar 15;144:61-67.|[2]Lee ST, et al. Stereoselective potencies and relative toxicities of coniine enantiomers. Chem Res Toxicol. 2008 Oct;21 (10) :2061-4.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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