(±) -Coniine

(±) -Coniine (2-Propylpiperidine) is a piperidine alkaloid and nAChR agonist (EC50=0.3 mM) . (±) -Coniine is acutely toxic to mice with an LD50 value of 7.7 mg/kg[1][2].

Product Specifications

CAS Number

[3238-60-6]

Product Name Alternative

2-Propylpiperidine

UNSPSC

12352005

Hazard Statement

H315-H319-H320

Target

NAChR

Type

Natural Products

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/racemic-coniine.html

Solubility

10 mM in DMSO

Smiles

CCCC1NCCCC1

Molecular Formula

C8H17N

Molecular Weight

127.23

Precautions

P264-P280-P302+P352-P305+P351+P338-P362

References & Citations

[1]B T Green, et al. Complete Inhibition of Fetal Movement in the Day 40 Pregnant Goat Model by the Piperidine Alkaloid Anabasine but Not Related Alkaloids. Toxicon. 2018 Mar 15;144:61-67.|[2]Lee ST, et al. Stereoselective potencies and relative toxicities of coniine enantiomers. Chem Res Toxicol. 2008 Oct;21 (10) :2061-4.