ST045849
OGT-IN-2 (compound 4) is a potent O-GlcNAc transferase (OGT) inhibitor, with IC50 values of 30 and 53 μM for sOGT and ncOGT, respectively[1].
Product Specifications
CAS Number
[442665-87-4]
Product Name Alternative
OGT-IN-2
UNSPSC
12352005
Target
Acyltransferase; OGT
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Neuronal Signaling
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ogt-in-2.html
Purity
99.82
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(C1)N(/C(SC1C(O)=O)=N/C(C=C2)=CC=C2Cl)CCC3(C[C@H](C4)C5)C[C@H]5C[C@H]4C3
Molecular Formula
C23H27ClN2O3S
Molecular Weight
446.99
References & Citations
[1]Gross BJ, et al. Discovery of O-GlcNAc transferase inhibitors. J Am Chem Soc. 2005 Oct 26;127 (42) :14588-9.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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