Mirogabalin-d4
Mirogabalin-d4 (DS5565-d4) is a deuterated compound of Mirogabalin , a ligand that selectively targets the voltage-sensitive calcium channel complex α2δ-1[1][2].
Product Specifications
Product Name Alternative
DS5565-d4
UNSPSC
12352211
Target
Calcium Channel; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling; Others
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
CCC1=C[C@H]2[C@](C([2H])([2H])C(O)=O)(C(N)([2H])[2H])C[C@H]2C1
Molecular Formula
C12H15D4NO2
Molecular Weight
213.31
References & Citations
[1]Vinik A, et al. Efficacy and safety of Mirogabalin (DS-5565) for the treatment of diabetic peripheral neuropathic pain: a randomized, double-blind, placebo- and active comparator-controlled, adaptive proof-of-concept phase 2 study. Diabetes Care. 2014 Dec.|[2]Hutmacher MM, et al. Exposure-response modeling of average daily pain score, and dizziness and somnolence, forMirogabalin (DS-5565) in patients with diabetic peripheral neuropathic pain. J Clin Pharmacol. 2016 Jan;56 (1) :67-77.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
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