EN40
EN40 is a potent, selective aldehyde dehydrogenase 3A1 (ALDH3A1) inhibitor as a covalent ligand, exhibits an IC50 value of 2 uM[1]
Product Specifications
CAS Number
[2094547-67-6]
UNSPSC
12352005
Target
Aldehyde Dehydrogenase (ALDH)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/en40.html
Purity
99.33
Solubility
DMSO : ≥ 100 mg/mL|Ethanol : 100 mg/mL (ultrasonic)
Smiles
C=CC(N1CCC(C)=C(C2=CC=CO2)C1)=O
Molecular Formula
C13H15NO2
Molecular Weight
217.26
References & Citations
[1]Counihan JL, et al.Chemoproteomics-Enabled Covalent Ligand Screening Reveals ALDH3A1 as a Lung Cancer Therapy Target.ACS Chem Biol. 2018 Aug 17;13 (8) :1970-1977
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ALDH3
Available Sizes
Curated Selection
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