Sarcosine-15N
Sarcosine-15N is the 15N-labeled Sarcosine. Sarcosine (N-Methylglycine), an endogenous amino acid, is a competitive glycine transporter type I (GlyT1) inhibitor and N-methyl-D-aspartate (NMDA) receptor co-agonist. Sarcosine increases the glycine concentration, resulting in an indirect potentiation of the NMDA receptor. Sarcosine is commonly used for the research of schizophrenia[1][2].
Product Specifications
Product Name Alternative
N-Methylglycine-15N; Sarcosin-15N
UNSPSC
12352211
Target
Endogenous Metabolite; GlyT
Type
Isotope-Labeled Compounds
Related Pathways
Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sarcosine-15n.html
Purity
99.92
Solubility
10 mM in DMSO|DMSO : 1mg/mL (ultrasonic) |H2O : 100mg/mL (ultrasonic)
Smiles
O=C(C[15NH]C)O
Molecular Formula
C3H7 15NO2
Molecular Weight
90.09
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Isoform
GlyT1
Available Sizes
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