What is the catalog number for 8-Bromo-cAMP?

The catalog number for 8-Bromo-cAMP is HY-12306A.

What sizes are available for 8-Bromo-cAMP?

8-Bromo-cAMP is available in the following size(s): 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg.

How many pack sizes does 8-Bromo-cAMP come in?

8-Bromo-cAMP is available in 7 different pack sizes.

Is 8-Bromo-cAMP in stock?

8-Bromo-cAMP is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures 8-Bromo-cAMP?

8-Bromo-cAMP is manufactured by QuantiMol.

What is the estimated delivery time for 8-Bromo-cAMP?

Estimated delivery time for 8-Bromo-cAMP is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for 8-Bromo-cAMP?

The safety data sheet for 8-Bromo-cAMP is available here: http://file.medchemexpress.com/batch_PDF/HY-12306A/8-Bromo-cAMP-SDS-MedChemExpress.pdf.

8-Bromo-cAMP

8-Bromo-cAMP (8-Br-Camp), a cyclic AMP analog, is an activator of cyclic AMP-dependent protein kinase (PKA) . 8-Bromo-cAMP has anti-proliferative and apoptotic effects against cancer cells[1][2].

Product Specifications

CAS Number

23583-48-4

Product Name Alternative

8-Br-Camp

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis; PKA

Type

Reference compound

Related Pathways

Apoptosis; Stem Cell/Wnt; TGF-beta/Smad

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/8-bromo-camp.html

Purity

99.48

Solubility

1 M NaOH : 100 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

OP1(O[C@@]2([H])[C@@H](O)[C@@H](O[C@]2([H])CO1)N3C(Br)=NC4=C3N=CN=C4N)=O

Molecular Formula

C10H11BrN5O6P

Molecular Weight

408.10

Precautions

H302, H315, H319, H335

References & Citations

[1]Wang Y, et al. A cyclic AMP analog, 8-Br-cAMP, enhances the induction of pluripotency in human fibroblast cells. Stem Cell Rev. 2011 Jun;7 (2) :331-41.|[2]Wang HM, et al. Dual effects of 8-Br-cAMP on differentiation and apoptosis of human esophageal cancer cell line Eca-109. World J Gastroenterol. 2005 Nov 7;11 (41) :6538-42.|[3]Baek MO, et al. Differential regulation of mTORC1 and mTORC2 is critical for 8-Br-cAMP-induced decidualization. Exp Mol Med. 2018 Oct 30;50 (10) :1-11. |[4]Wang S, et al. Angiogenesis and vasculogenic mimicry are inhibited by 8-Br-cAMP through activation of the cAMP/PKA pathway in colorectal cancer. Onco Targets Ther. 2018 Jul 2;11:3765-3774