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(Rac) -AB-423

(Rac) -AB-423 (DVR-23) is an anti-HBV candidate compound with promising anti-HBV activity. (Rac) -AB-423 showed no induction of CYP1A2, CYP3A4, or CYP2B6 enzyme activity at high concentrations. (Rac) -AB-423 exhibited desirable pharmacokinetic properties, enabling good systemic exposure and high oral bioavailability. (Rac) -AB-423 achieved more than 2 log viral load reduction in the hydrodynamic injection (HDI) HBV mouse model[1].

Product Specifications

CAS Number

422547-55-5

Product Name Alternative

DVR-23

UNSPSC

12352005

Target

HBV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/rac-ab-423.html

Smiles

O=C(NC1=CC=C(F)C(F)=C1)C2=CC(S(=O)(NC(C)CC)=O)=CC=C2F

Molecular Formula

C17H17F3N2O3S

Molecular Weight

386.39

References & Citations

[1]3- ((R) -4- (((R) -6- (2-Bromo-4-fluorophenyl) -5- (ethoxycarbonyl) -2- (thiazol-2-yl) -3,6-dihydropyrimidin-4-yl) methyl) morpholin-2-yl) propanoic Acid (HEC72702), a Novel Hepatitis B Virus Capsid Inhibitor Based on Clinical Candidate GLS4

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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