Garlic oil
Garlic oil contains various organosulfur compounds with anticancer activities. Garlic oil can significantly activate apoptosis in lung tissue induced by NNK. Furthermore, Garlic oil can markedly reduce NNK-induced DNA damage and prevent the occurrence of lung cancer by inducing the expression of phase II drug-metabolizing enzymes (HO-1, NQO-1, and GSTA1).
Product Specifications
CAS Number
8000-78-0
UNSPSC
12352211
Target
Apoptosis; Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/garlic-oil.html
Smiles
[Garlicoil]
References & Citations
[1]Zhang L, et al. Garlic oil blocks tobacco carcinogen 4- (methylnitrosamino) -1- (3-pyridyl) -1-butanone (NNK) -induced lung tumorigenesis by inducing phase II drug-metabolizing enzymes[J]. Food and Chemical Toxicology, 2021, 157: 112581.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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