BMS-332
Product Specifications
UNSPSC Description
BMS-332 is adualDGKα/ζlipid kinase inhibitor, with theIC50of 0.005 (DGKα) and 0.001 μM (DGKζ)[1].
Target Antigen
DGK
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bms-332.html
Solubility
DMSO : 14.29 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
CN(C1=CC=C(C#N)N=C1C(N2C[C@@H](C)N(C(C3=CC=C(F)C=C3)C4=CC=C(F)C=C4)C[C@@H]2C)=C5)C5=O
Molecular Weight
499.55
References & Citations
[1]Wichroski M, et al. DGKα/ζ inhibitors combine with PD-1 checkpoint therapy to promote T cell-mediated antitumor immunity. Sci Transl Med. 2023;15(719):eadh1892.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-149667/BMS-332-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-149667/BMS-332-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2407892-15-1
Available Sizes
Curated Selection
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