PPACK II (diTFA)
PPACK II diTFA is an irreversible and specific glandular and plasma kallikreins inhibitor[1].
Product Specifications
CAS Number
649748-23-2
UNSPSC
12352005
Target
Kallikrein
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/ppack-ii-ditfa.html
Purity
97.21
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(O)C(F)(F)F.O=C(O)C(F)(F)F.N=C(N)NCCC[C@@H](C(CCl)=O)NC([C@@H](NC([C@H](N)CC1=CC=CC=C1)=O)CC2=CC=CC=C2)=O
Molecular Formula
C29H35ClF6N6O7
Molecular Weight
729.07
References & Citations
[1]Kentaro Takayama, et al. Identification of a degrading enzyme in human serum that hydrolyzes a C-terminal core sequence of neuromedin U. Biopolymers. 2016 Nov 4;106 (4) :440-5.|[2]Alexander Belenky, et al. The effect of class-specific protease inhibitors on the stabilization of B-type natriuretic peptide in human plasma. Clin Chim Acta. 2004 Feb;340 (1-2) :163-72.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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