Methylophiopogonanone B

Methylophiopogonanone B, homoisoflavonoid, is extracted from the root of Ophiopogon japonicas, shows high antioxidant ability[1]. Methylophiopogonanone B increases GTP-Rho and acts via the Rho signaling pathway, inducing cell morphological change via actin cytoskeletal reorganization, including dendrite retraction and stress fiber formation[2].

Product Specifications

CAS Number

[74805-91-7]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Ras

Type

Natural Products

Related Pathways

GPCR/G Protein; MAPK/ERK Pathway

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/methylophiopogonanone-b.html

Purity

99.84

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1[C@H](CC2=CC=C(OC)C=C2)COC3=C(C)C(O)=C(C)C(O)=C13

Molecular Formula

C19H20O5

Molecular Weight

328.36

Precautions

H302, H315, H319, H335

References & Citations

[1]Wang Y, et al. Homoisoflavonoids and the Antioxidant Activity of Ophiopogon japonicus Root.|[2]Ito Y, et al. A novel agent, methylophiopogonanone B, promotes Rho activation and tubulin depolymerization. Mol Cell Biochem. 2007 Mar;297 (1-2) :121-9. Epub 2006 Oct 7.