(+) -trans-C75
(+) -trans-C75 ((+) -C75) is an enantiomer of C75 (a fatty acid synthase inhibitor). (+) -trans-C75 is less potent than the racemic mixture or the (-) enantiomer in enhancing the cancer-killing ability of ionizing radiation. (+) -trans-C75 inhibits CPT1 and is an anorectic agent[1][2].
Product Specifications
CAS Number
1234694-20-2
Product Name Alternative
(+) -C75
UNSPSC
12352005
Target
Mitochondrial Metabolism
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/plus-trans-c75.html
Smiles
O=C([C@@H](C1=C)[C@@H](CCCCCCCC)OC1=O)O
Molecular Formula
C14H22O4
Molecular Weight
254.32
References & Citations
[1]Rae C, et al. Differential in radiosensitizing potency of enantiomers of the fatty acid synthase inhibitor C75. Chirality. 2017 Jan;29 (1) :10-13.|[2]Makowski K, et al. Differential pharmacologic properties of the two C75 enantiomers: (+) -C75 is a strong anorectic drug; (-) -C75 has antitumor activity. Chirality. 2013 May;25 (5) :281-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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