(+) -trans-C75

(+) -trans-C75 ((+) -C75) is an enantiomer of C75 (HY-12364) (a fatty acid synthase inhibitor) . (+) -trans-C75 is less potent than the racemic mixture or the (-) enantiomer in enhancing the cancer-killing ability of ionizing radiation. (+) -trans-C75 inhibits CPT1 and is an anorectic agent[1][2].

Product Specifications

CAS Number

[1234694-20-2]

Product Name Alternative

(+) -C75

UNSPSC

12352005

Target

Mitochondrial Metabolism

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/plus-trans-c75.html

Smiles

O=C([C@@H](C1=C)[C@@H](CCCCCCCC)OC1=O)O

Molecular Formula

C14H22O4

Molecular Weight

254.32

References & Citations

[1]Rae C, et al. Differential in radiosensitizing potency of enantiomers of the fatty acid synthase inhibitor C75. Chirality. 2017 Jan;29 (1) :10-13.|[2]Makowski K, et al. Differential pharmacologic properties of the two C75 enantiomers: (+) -C75 is a strong anorectic drug; (-) -C75 has antitumor activity. Chirality. 2013 May;25 (5) :281-7.