Zn (II) Mesoporphyrin IX

Zn (II) Mesoporphyrin IX (ZnMP) is a specific activator of ABCB10, significantly increasing its ATPase activity and acting as a substrate for ABCB10 in heme synthesis. Zn (II) Mesoporphyrin IX may promote the transcription of hemoglobinization genes by facilitating the degradation of the Bach1 repressor. Zn (II) Mesoporphyrin IX aids in studying the potential roles of ABCB10 in heme synthesis, oxidative stress protection, hepatitis C, and other areas[1][2].

Product Specifications

CAS Number

[14354-67-7]

Product Name Alternative

ZnMP

UNSPSC

12352200

Hazard Statement

H302, H315, H319, H335

Target

Biochemical Assay Reagents

Type

Biochemical Assay Reagents

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/zn-ii-mesoporphyrin-ix.html

Purity

95.0

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(CCC1=C(C)C2=CC3=C(C)C(CC)=C4C=C5C(C)=C(CC)C6=[N]5[Zn+2]([N-]34)([N-]78)[N]2=C1C=C8C(CCC(O)=O)=C(C)C7=C6)O

Molecular Formula

C34H36N4O4Zn

Molecular Weight

630.05

Precautions

H302, H315, H319, H335

References & Citations

[1]Martinez M, et al. Stimulation of the human mitochondrial transporter ABCB10 by zinc-mesoporphrin. PLoS One. 2020 Nov 30;15 (11) :e0238754. |[2]Clark ER, et al. Photosensitized H2 generation from "one-pot" and "two-pot" assemblies of a zinc-porphyrin/platinum nanoparticle/protein scaffold. Dalton Trans. 2016 Jan 14;45 (2) :630-8.