Tempol

Tempol is a general superoxide dismutase (SOD) -mimetic agent that efficiently neutralizes reactive oxygen species (ROS) .

Product Specifications

CAS Number

[2226-96-2]

Product Name Alternative

4-Hydroxy-TEMPO

UNSPSC

12352005

Hazard Statement

H302, H318, H402

Target

Autophagy; Reactive Oxygen Species (ROS)

Type

Reference compound

Related Pathways

Autophagy; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Tempol.html

Purity

99.78

Solubility

H2O : 5.56 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

[O]N1C(C)(C)CC(O)CC1(C)C

Molecular Formula

C9H18NO2

Molecular Weight

172.24

Precautions

H302, H318, H402

References & Citations

[1]Vilar-Pereira G, et al. Resveratrol Reverses Functional Chagas Heart Disease in Mice. PLoS Pathog. 2016 Oct 27;12 (10) :e1005947.|[2]Chatterjee PK, et al. Tempol, a membrane-permeable radical scavenger, reduces oxidant stress-mediated renal dysfunction and injury in the rat. Kidney Int. 2000 Aug;58 (2) :658-73.