Tempol
Tempol is a general superoxide dismutase (SOD) -mimetic agent that efficiently neutralizes reactive oxygen species (ROS) .
Product Specifications
CAS Number
2226-96-2
Product Name Alternative
4-Hydroxy-TEMPO
UNSPSC
12352005
Hazard Statement
H302, H318, H402
Target
Autophagy; Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Autophagy; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Tempol.html
Purity
99.78
Solubility
H2O : 5.56 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
[O]N1C(C)(C)CC(O)CC1(C)C
Molecular Formula
C9H18NO2
Molecular Weight
172.24
Precautions
H302, H318, H402
References & Citations
[1]Vilar-Pereira G, et al. Resveratrol Reverses Functional Chagas Heart Disease in Mice. PLoS Pathog. 2016 Oct 27;12 (10) :e1005947.|[2]Chatterjee PK, et al. Tempol, a membrane-permeable radical scavenger, reduces oxidant stress-mediated renal dysfunction and injury in the rat. Kidney Int. 2000 Aug;58 (2) :658-73.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Reference compound1
Clinical Information
Phase 3
Available Sizes
Frequently Asked Questions
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