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MMH2-NR

MMH2-NR a negtive control of MMH2. MMH2 is a CUL4-associated factor (DCAF16) -based bromodomain protein 4 (BRD4) degrader[1].

Product Specifications

UNSPSC

12352005

Target

Epigenetic Reader Domain; Molecular Glues

Type

Reference compound

Related Pathways

Epigenetics; PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mmh2-nr.html

Purity

98.72

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC1=C(C)SC2=C1C(C3=CC=C(NS(CC)(=O)=O)C=C3)=N[C@@H](CC(OC(C)(C)C)=O)C4=NN=C(C)N42

Molecular Formula

C25H31N5O4S2

Molecular Weight

529.67

References & Citations

[1]Yen-Der Li, et al. Template-assisted covalent modification of DCAF16 underlies activity of BRD4 molecular glue degraders. bioRxiv. 2023 Feb 15:2023.02.14.528208.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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