UBP301 (hydrochloride)
UBP301 hydrochloride is a potent and selective antagonist of kainate receptor with IC50 and KD of 164 μM and 5.94 μM, respectively. UBP301 hydrochloride has ～30-fold selectivity of kainate receptor over AMPA receptor. UBP301 hydrochloride is the derivative of willardiine[1].
Product Specifications
UNSPSC
12352005
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ubp301-hydrochloride.html
Purity
97.45
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N(C=C(I)C1=O)C[C@H](N)C(O)=O)N1CC2=CC=C(C(O)=O)C=C2.[H]Cl
Molecular Formula
C15H15ClIN3O6
Molecular Weight
495.65
References & Citations
[1]More JC, et al. Structural requirements for novel willardiine derivatives acting as AMPA and kainate receptor antagonists. Br J Pharmacol. 2003;138 (6) :1093-1100.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS1008897-01 0.02 mg (E-Coli)
Recombinant Haemophilus influenzae Purine nucleoside phosphorylase DeoD-type (deoD)
Sign In for Pricing
View Details